Identification, separation, isolation and characterization of major impurities in some anticancer and antipsychotic drugs
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Synthesis, Characterization and In-vitro Evaluation of Novel Naphthoquinone Derivatives and Related Imines: Identification of New Anticancer Leads
Quinones such as 1,4-naphthoquinones are abundant in nature and naphthoquinone based natural products are known to possess anticancer activity. This pharmacophore is known to convey anticancer activity to some drugs such as streptonigrin, mitomycin A, etc. We synthesized and characterized different classes of naphthoquinone derivatives including bis naphthoquinone, 2-arylaminonaphthoquinone, be...
متن کاملSynthesis, Characterization and In-vitro Evaluation of Novel Naphthoquinone Derivatives and Related Imines: Identification of New Anticancer Leads
Quinones such as 1,4-naphthoquinones are abundant in nature and naphthoquinone based natural products are known to possess anticancer activity. This pharmacophore is known to convey anticancer activity to some drugs such as streptonigrin, mitomycin A, etc. We synthesized and characterized different classes of naphthoquinone derivatives including bis naphthoquinone, 2-arylaminonaphthoquinone, be...
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The occurrences of huge reserves of garnet deposits have been reported from different parts of Iran specially those of Kohe-E-Gabri area which is very high grade in nature. These deposits can not be directly used as abrasives, filter aid and many others because of some impurities present. To know the mineralogical composition, the type of garnet, the shape of the particles, the chemical charact...
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متن کاملIdentification, separation and characterization of impurities present in olanzapine drug substance and the impurities enriched through oxidative degradation
6.1.0 Introduction Olanzapine, chemically known as 2-Methyl-4-(4-methyl-1-piperazinyl)-10Hthieno [2, 3-b] [1, 5] benzodiazepine, is a potential antipsychotic agent used in chemotherapy. It has been approved by the food and drug administration (FDA) and it is one of the most commonly used atypical anti psychotics. It is used in the treatment of schizophrenia, acute mania in bipolar disorder, agi...
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تاریخ انتشار 2014